Glucosamine

What is it?

Glucosamine sulfate is a chemical found in our bodies. It is used by the body to form components of ligaments, tendons, cartilage and fluid that surround joints. As we age, the cartilage and the fluid that cushion the joints from friction gets worn out resulting in pain in osteoarthritis. Glucosamine is supposed to increase the joint fluid and cartilage to slow down the process of degeneration. It is now used as supplements made from the shell of shellfish.

Benefits

There have been scientific evidence that glucosamine helps in osteoarthritis of knees and also temporomandibular joint arthritis (jaw-bone pain).

However, there are currently insufficient evidence based studies that prove its effectiveness in certain conditions like weight loss and glaucoma. More studies are required to verify such claims. 

Possible side effects

Glucosamine at appropriate dose is generally safe for most adults. But there are some possible side effects include nausea, heartburn, diarrhea and constipation. Those who are allergic to shellfish should not take supplements derived from the shell of shellfish to avoid allergic reactions.

It is not recommended for lactating/pregnant women as it may be linked to possible birth defects during pregnancy.

Drug-drug interactions

1. Warfarin: Glucosamine may increase the bleeding tendencies of warfarin

2. Cancer drugs: some scientists think that glucosamine may reduce the effectiveness of anti-cancer drugs.

Dosage

The following are suggested dosages of glucosamine for certain medical conditions. Please follow the instructions on product label and if in doubt consult your doctor first.

For osteoarthritis: take 500 mg 3 times daily or 1500mg once daily

For temporomandibular arthritis: take 500 mg 3 times daily

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